Pre-Course Assessment: Tutorial Course for the ASCPiCertification Exam

Hematology [H(ASCPi)]

Samir Awadallah, PhD, MLS(ASCP), CLS(NCA)

Tutorial Course for the ASCPi Certification Exam Hematology [H(ASCPi)]

Pre-Assessment Questions

Purpose of this pre-assessment exam is to evaluate the competence and knowledge of students of different aspects and principles of the hematology subject. The questions involves topics in basic and advanced hematology and coagulation that are covered by the ASCP Certification exam in Hematology [H(ASCP) and SH(ASCP)].

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1. When compared to normal adult CBC values, normal values for neonates and children differ considerably with the exception of:(Required)

2. The following are true for hemoglobin measurement by automated analyzers:(Required)

3. Which of the following is a true statement?(Required)

4. Causes of falsely elevated hemoglobin levels by the spectrophotometric method include all of the following except:(Required)

5. Which of the following equations is correct to calculate MCH values?(Required)

6. One indication for warming the blood and repeating the CBC test is elevated:(Required)

7. When the uncorrected WBC count is higher than the corrected WBC count, the most likely cause is:(Required)

8. Causes of false low platelet count (pseudothrombocytopenia) include all of the following except:(Required)

9. When a peripheral smear slide appears blue to the naked eye, a likely possibility is:(Required)

10. Effect of EDTA on platelets include:(Required)

11. Regarding reticulocytes:(Required)

12. Mean cell volume (MCV) is calculated by using the following formula:(Required)

13. Calculate the mean cell hemoglobin concentration (MCHC) by using the following values:(Required)
Hgb: 15 g/dL (150 g/L) Hct: 47 mL/dL (0.47); RBC: 4.50 × 106/μL (4.50 × 1012/L)

14. A manual white blood cell (WBC) count was performed. In total 36 cells were counted in all 9-mm2 squares of a Neubauer-ruled hemacytometer. A 1:10 dilution was used. What is the WBC count?(Required)

15. When an erythrocyte containing iron granules is stained with Prussian blue, the cell is called a:(Required)

16. A 7.0-mL ethylenediaminetetraacetic acid (EDTA) tube is received in the laboratory containing only 2.0 mL of blood. If the laboratory is using manual techniques, which of the following tests will most likely be erroneous?(Required)

17. If a patient has a reticulocyte count of 7% and Hct of 20%, what is the corrected reticulocyte count?(Required)

18. A decreased osmotic fragility test would be associated with which of the following conditions?(Required)

19. What effect would using a buffer at pH 6.0 have on a Wright-stained smear?(Required)

20. Which of the following erythrocyte inclusions can be visualized with supravital stain but cannot be detected on a Wright-stained blood smear?(Required)

21. A falsely elevated Hct is obtained. Which of the following calculated values will not be affected?(Required)

22. SITUATION: RBC indices obtained on an anemic patient are as follows: MCV 88 μm3 (fL); MCH 30 pg; MCHC 34% (0.340). The RBCs on the peripheral blood smear would appear:(Required)

23. All of the following factors may influence the erythrocyte sedimentation rate (ESR) except:(Required)

24. The Coulter principle for counting of cells is based on the fact that:(Required)

25. A correction is necessary for WBC counts when NRBCs are seen on the peripheral blood because:(Required)

26. Using an electronic cell counter analyzer, an increased RDW should correlate with:(Required)

27. Given the following values, which set of RBC indices suggests spherocytosis?(Required)

28. Which of the following statistical terms reflects the best index of precision when comparing two complete blood count (CBC) parameters?(Required)

29. Which of the following is considered a normal Hgb?(Required)

30. Which is the first stage of erythrocytic maturation in which the cytoplasm is pink because of the formation of Hgb?(Required)

31. Autoagglutination of RBCs at room temperature can cause which of the following abnormal test results?(Required)

32. Review the scatterplot of WBCs shown. Which section of the scatterplot denotes the number of monocytes?(Required)
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33. What is the presumptive diagnosis?(Required)
Review the following scatterplot, histograms, and automated values for a 21-year-old college student WBC differential: 5 band neutrophils; 27 segmented neutrophils; 60 atypical lymphocytes; 6 monocytes; 1 éosinophile; 1 basophile
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34. What is the presumptive diagnosis?(Required)
Review the following scatterplot, histograms, and automated values for a 61-year-old woman. WBC differential: 14 band neutrophils; 50 segmented neutrophils; 7 lymphocytes; 4 monocytes; 10 metamyelocytes; 8 myelocytes; 1 promyelocyte; 3 eosinophils; 3 basophils; 2 NRBCs/100 WBCs
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35. The following are features of normal erythropoiesis except:(Required)

36. Which of the following is an effective marker for erythroid precursors?(Required)

37. Regarding erythropoiesis, which is true:(Required)

38. All of the following regarding erythropoiesis are true except:(Required)

39. This image is for blood smear showing the results for an acid elution test. The main purpose of this test is to detect:(Required)
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40. With what type of anemia are these results associated?(Required)
A patient had the following results: RBC 2.90 x 106/mcL MCV 76 fL Hb 6.2 g/dL MCH 21 pg Hct 22.0% MCHC 28 g/dL Serum iron 45 mcg/dL sTfR 28.5 nmol/L

41. Iron deficiency may result in the misdiagnosis of:(Required)

42. Which of the following tests for hereditary spherocytosis has the highest sensitivity and specificity?(Required)

43. HbH disease is characterized by:(Required)

44. Which factors are part of the intrinsic system of the coagulation cascade?(Required)

45. A differential was performed on a asymptomatic patient. The differential included 60% neutrophils, 55 of which had 2 lobs and 5 had 3 lobes. There were no other abnormalities. This consistent with which of the following anomalies?(Required)

46. The large cell indicated by the arrow in the image below is a:(Required)
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